It is also the parent compound of its own structural class, the substituted amphetamines, which includes prominent substances such as bupropion, cathinone, MDMA, and methamphetamine. Īmphetamine belongs to the phenethylamine class. Recreational doses are generally much larger than prescribed therapeutic doses and carry a far greater risk of serious side effects. Very high doses can result in psychosis (e.g., delusions and paranoia) which rarely occurs at therapeutic doses even during long-term use. Addiction is a serious risk with heavy recreational amphetamine use, but is unlikely to occur from long-term medical use at therapeutic doses. ![]() Larger doses of amphetamine may impair cognitive function and induce rapid muscle breakdown. It induces physical effects such as improved reaction time, fatigue resistance, and increased muscle strength. Īt therapeutic doses, amphetamine causes emotional and cognitive effects such as euphoria, change in desire for sex, increased wakefulness, and improved cognitive control. Amphetamine increases monoamine and excitatory neurotransmission in the brain, with its most pronounced effects targeting the norepinephrine and dopamine neurotransmitter systems. Currently, pharmaceutical amphetamine is prescribed as racemic amphetamine, Adderall, dextroamphetamine, or the inactive prodrug lisdexamfetamine. The first amphetamine pharmaceutical was Benzedrine, a brand which was used to treat a variety of conditions. It is a prescription drug in many countries, and unauthorized possession and distribution of amphetamine are often tightly controlled due to the significant health risks associated with recreational use. Amphetamine is also used as an athletic performance enhancer and cognitive enhancer, and recreationally as an aphrodisiac and euphoriant. Historically, it has been used to treat nasal congestion and depression. The term is frequently used informally to refer to any combination of the enantiomers, or to either of them alone. Amphetamine properly refers to a specific chemical, the racemic free base, which is equal parts of the two enantiomers in their pure amine forms. Amphetamine was discovered in 1887 and exists as two enantiomers: levoamphetamine and dextroamphetamine. It is also commonly used as a recreational drug. ![]() Alternatively, you can choose any of the predefined session durations in Amphetamine’s menu by clicking Amphetamine’s icon in the system menu bar and selecting a duration, app-based session, or file-download-based session.Amphetamine (contracted from alpha- methyl phen ethyl amine) is a strong central nervous system (CNS) stimulant that is used in the treatment of attention deficit hyperactivity disorder (ADHD), narcolepsy, and obesity. Right-click Amphetamine’s icon in the system menu bar again to end the session. Right-click Amphetamine’s icon in the system menu bar to start a session that will run using your default duration (indefinitely by default change in Preferences → Sessions → Non-Trigger Sessions). Manual session end is done by selecting End Current Session from Amphetamine’s menu, or by using a hot key.Īt its most basic, Amphetamine is an on/off utility. Manual session start is done by selecting a duration from Amphetamine’s menu in the system menu bar, or by using hot keys. Automatic session start/end is done through the Triggers feature. ![]() When Amphetamine is keeping your Mac awake, this is referred to as a “session.” You can start and end a session, either manually or automatically. From the menu you can manually start or end a session, quickly change some of Amphetamine’s many preferences/settings, contact support, and quit the app. Clicking on this icon will cause Amphetamine’s menu to show. This option can be managed in Amphetamine’s Preferences.Īmphetamine’s default icon in the system menu bar is a round segmented pill. It can also present its icon in the Dock, but many people choose to hide the Dock icon. Amphetamine is highly customizable, allowing you to keep your Mac awake for a specified duration, or when conditions are met like a certain app running, while a file is downloading, or while a USB device is connected.Īmphetamine runs from your system menu bar. Modified on: Tue, 18 Feb, 2020 at 11:13 AMĪmphetamine is a macOS utility that can keep your Mac awake during times or situations you define.
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